Properties
Description
10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor with potent anti-tumor activity.
Molecular Formula
C20H16N2O5
Source
The fruit of Camptotheca acuminata
Form
Light yellow crystalline powder
Purity
>99%, determined by HPLC.
Solubility
It is insoluble in water, soluble in dilute alkali solution, hardly soluble in methanol, chloroform, acetone, slightly soluble in methanol-chloroform mixed solvent.
Identity
Confirmed by NMR and MS.
Applications
10-hydroxycamptothecin can be usedis used in the research of gastric cancer, liver cancer, head and neck cancer and leukemia, etc.
