Properties
Description
12-O-Tetradecanoyl phorbol-13-acetate, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets NF-κB, and PKC.
Molecular Formula
C36H56O8
Targets
NF-κB; PKC: 11.7 nM
Solubility
DMSO: 94 mg/mL (152.38 mM); Water: insoluble; Ethanol: 94 mg/mL
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
12-O-Tetradecanoyl phorbol-13-acetate can be used to help develop potential therapeutic strategies for certain diseases, such as inflammatory disease, fibrotic diseases, and cancer.
Storage
Store at -20℃, and keep desiccated.
