5'-O-DMTr-2'-ara-OAc-A(Bz)-3'-CE-phosphoramidite

Synonym: N6-Benzoyl-(5'-O-(4,4'-dimethoxytrityl)-2'-O-acetyl-arabinoadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Product Size

25 mg; 50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

5'-O-DMTr-2'-ara-OAc-A(Bz)-3'-CE-phosphoramidite has an -N6-benzoyl-arabinosylunit attached to the end of the oligonucleotide chain by a phosphoramidate bond.

Molecular Weight

915.98

Molecular Formula

C₄₉H₅₄N₇O₉P

Form

Colorless to light yellow crystalline or white, off-white to light yellow amorphous dry powder

Purity

≥95%, determined by HPLC.

Applications

5'-O-DMTr-2'-ara-OAc-A(Bz)-3'-CE-phosphoramidite is commonly used as a reagent for splicing and chain extension, where nucleotide chain synthesis is achieved by reacting with a nucleophilic reagent via a nucleophilic substitution reaction.

Storage

Store at -20°C.

Safety Information

Personal Protective Equipment

Gloves, eyeshields, N95 mask