Properties
Description
5'-O-DMTr-2'-O-Me-A(iBu) is a modified adenosine derivative containing a 5'-O-trimethylsilyl (DMTr) protecting group and a 2'-O-methyl modification, also with an isobutyl (iBu) side chain.
Molecular Formula
C36H39N5O7
Form
White to off-white powder
Purity
≥98%, determined by HPLC.
Applications
5'-O-DMTr-2'-O-Me-A(iBu) is commonly used to synthesize modified RNA or DNA sequences to improve the stability and affinity of the molecule.