Properties
Description
5'-O-DMTr-2'-O-Me-G(Ac) PACE is a modified guanosine with a DMTr (Dimethoxytrityl) protecting group at the 5' end and an O-methyl modification at the 2' end.
Molecular Formula
C47H58N7O10P
Form
White to pale yellow solid
Purity
≥98%, determined by HPLC.
Applications
5'-O-DMTr-2'-O-Me-G(Ac) PACE can be used to synthesize antisense oligonucleotides and RNA interference probes.