5'-O-DMTr-2'-O-MOE-5-Me-U-3'-methoxy-phosphoramidite

Name: 5'- O -DMTr-2'- O -MOE-5-Me-U-3'-methoxy-phosphoramidite
SKU: X24-09-LY024

Synonym: 5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-uridine-3'-methoxy-phosphoramidite

Product Size

25 mg; 50 mg; 100 mg; 250 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

5'-O-DMTr-2'-O-MOE-5-Me-U-3'-methoxy-phosphoramidite is a methoxyphosphoramidite compound containing a 5'-O-DMTr protecting group, 2'-O-MOE modification, and 5-methyluracil (U).

Molecular Weight

779.87

Molecular Formula

C₄₁H₅₄N₃O₁₀P

Form

White, off-white to faint yellow powder, free from visible foreign matter

Purity

≥98%, determined by HPLC.

Applications

5'-O-DMTr-2'-O-MOE-5-Me-U-3'-methoxy-phosphoramidite can be used to synthesize RNA-based molecules suitable for the construction of small interfering RNAs (siRNAs) and other forms of RNA-interfering drugs.