Properties
Description
5'-O-DMTr-2'-O-TBDMS-G(Ac)-3'-CE-phosphoramidite is a modified nucleotide with the 5'-end protected by dimethoxytrityl and the 2'-end is tert-butyldimethylsilyl containing acetyl (Ac) as a side chain.
Molecular Formula
C48H64N7O9PSi
Form
White, off-white to yellow powder, free from visible foreign matter
Purity
≥97%, determined by HPLC.
Applications
5'-O-DMTr-2'-O-TBDMS-G(Ac)-3'-CE-phosphoramidite is mainly used in DNA synthesis, especially in the synthesis of oligonucleotides with specific modifications to improve their stability in organisms.