5'-O-DMTr-2'-O-TBDMS-U-3'-methoxy-phosphoramidite

Name: 5'- O -DMTr-2'- O -TBDMS-U-3'-methoxy-phosphoramidite
SKU: X24-09-LY039

Synonym: 5'-O-(4, 4'-Dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-uridine-3'-methoxy-phosphoramidite

Product Size

5 mg; 10 mg; 25 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

5'-O-DMTr-2'-O-TBDMS-U-3'-methoxy-phosphoramidite is a modified uridine with DMTr protection at the 5'-end, TBDMS at the 2'-end, and methoxy (Methoxy) modification at the 3'-end.

Molecular Weight

822.02

Molecular Formula

C₄₃H₆₀N₃O₉PSi

Form

White, off-white to faint yellow powder, free from visible foreign matter

Purity

≥98%, determined by HPLC.

Applications

5'-O-DMTr-2'-O-TBDMS-U-3'-methoxy-phosphoramidite can be used to synthesize RNA molecules, especially in the manufacture of functional nmRNAs such as vaccines or gene therapy.