Properties
Description
5'-O-DMTr-2'-O-TMBTM-A(Bz)-3'-O-succinate is a derivative of adenine (A) nucleotide with a dimethylbenzyl protected (DMTr) group at the 5'-end, a 2'-O-substituted (TMBTM), and a succinate group at the 3'-end. The formation of triethylamine salt enhances its solubility and makes it suitable for synthesis.
Molecular Formula
C53H53N5O13S
Form
White to off-white powder
Purity
≥98%, determined by HPLC.
Applications
5'-O-DMTr-2'-O-TMBTM-A(Bz)-3'-O-succinate can be used to synthesize adenine-containing oligonucleotides.