Properties
Description
5'-O-DMTr-2'-O-TOM-C(Ac) phosphoramidite is a modified cytosine (C) phosphoramidite compound with a DMTr protecting group at the 5' end and a TOM protecting group at the 2' end along with an acetate group (Ac).
Molecular Formula
C51H72N5O10PSi
Form
White to off-white powder
Purity
≥98%, determined by HPLC.
Applications
5'-O-DMTr-2'-O-TOM-C(Ac) phosphoramidite is used in the synthesis of cytosine-containing nucleic acid sequences, especially as a precursor for phosphodiester bonds in the total synthesis of RNA and DNA.