Properties
Description
5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur contains specific protecting groups (Ts and TBDMS), and a C-locked uracil derivative.
Molecular Formula
C23H32N2O8SSi
Form
White, off-white to faint yellow powder
Purity
≥98%, determined by HPLC.
Applications
5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur is mainly applied to the synthesis of oligonucleotides, especially in the design of RNA molecules with specific biological functions or anti-degradation properties, which enhances the tolerance and stability of the molecules.