Properties
Description
A-3 hydrochloride blocks the function of Smad proteins in the TGF-β signaling pathway. It targets CK1, CK2, PKA, and PKC.
Molecular Formula
C12H14Cl2N2O2S
Targets
CK1: 80 μM; CK2: 5.1 μM; PKA: 4.3 μM; PKC: 47 μM
Applications
A-3 hydrochloride can be used as a modulator of neurotransmitter receptors or ion channels, making it useful for investigating synaptic transmission, neuronal excitability, and neurological disorders.