CD BioGlyco provides comprehensive Pharmaceutical and Biological Analysis Services to provide clients with accurate and reliable data support. As one of the important services, we are committed to providing high-quality Pharmaceutical Excipient Analysis Services tailored to the specific needs of our clients. One area where we excel is acacia analysis service. Acacia as a pharmaceutical excipient is a dried colloidal exudate or spray-dried powder obtained from the branches of acacia senegal (Linne) Willdenow or similar tree species of the same genus. Acacia plays an important role in pharmaceutical preparations and has various functions such as thickening, stabilization, and emulsification. Acacia is also highly biocompatible and safe. As a natural product, it has good compatibility with human tissues and is not likely to cause allergic reactions or adverse reactions.
Our total ash determination follows the following steps:
Our acid-insoluble ash determination procedure is as follows:
Our weight loss on drying is measured as follows:
Our heavy metal analysis uses the following methods:
Our arsenic salt analysis mainly uses the following methods:
Our microbial limit checks follow these steps:
Technology: Characterization of physical and chemical properties
Journal: BioMed Research International
IF: 3.258
Published: 2021
Results: The authors of the research conducted an examination aimed at assessing the binding effect of Acacia etbaica (AET) gum in granule and tablet forms using paracetamol as an exemplar drug. Through physicochemical characterization, it was discovered that the gum lacked tannins and dextrin and exhibited an acidic pH. The moisture content and total ash values were within the prescribed standards. The authors also discovered that the gum was soluble in both cold and hot water but insoluble in organic solvents, demonstrating a shear-thickening viscosity profile with outstanding flow and compressibility properties. Granules produced using AET gum and reference binders exhibited favorable particle size distribution as well as exceptional flow and compressibility categories. All manufactured tablets met pharmacopoeial specifications in terms of weight uniformity, thickness, and disintegration duration. Tablets that were formulated with AET gum and acacia BP (ABP) satisfied the official standard for friability at binder concentrations exceeding 2%. The drug release characteristics of every batch formulated with AET, polyvinylpyrrolidone (PVP), and ABP met the pharmacopeial standard.
Fig.1 Effect of binder concentration on the crushing strength (left) and tensile strength (right) of paracetamol tablets prepared at different concentrations of AET, PVP, and ABP. (Desta, et al., 2021)
Due to its unique colloidal properties and adhesion, acacia plays a role in protecting and encapsulating the active ingredients of drugs in pharmaceutical preparations, thereby slowing down the release rate of drugs in the gastrointestinal tract and improving the bioavailability of drugs. This slow-release feature helps the drug continue to act in the body and increase its effectiveness.
CD BioGlyco provides comprehensive and accurate acacia analysis services, including but not limited to the determination of total ash, acid-insoluble ash, loss on drying, heavy metals, arsenic salts, and microbiological limits. In addition, we also provide related customized services. Please feel free to contact us if you are interested in our acacia analysis service.
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