Acetyl-CoA carboxylase inhibitor, PF-05175157, Purity ≥98%

Synonym: 1301214-47-0; PF05175157; PF 05175157; 1'-(2-Methyl-3H-benzimidazole-5-carbonyl)-1-propan-2-ylspiro[4,6-dihydroindazole-5,4'-piperidine]-7-one; Acetyl-CoA carboxylase inhibitor

MDL: MFCD28502250
CAS Number: 1301214-47-0
Compound CID: 52934180

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-05175157, soluble in DMSO, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting acetyl-CoA carboxylase. The molecular weight of the compound is 405.49, and its molecular formula is C₂₃H₂₇N₅O₂.

Molecular Weight

405.49

Molecular Formula

C₂₃H₂₇N₅O₂

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 28 mg/mL (69.05 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-05175157 displays the significant potential to act as an effective inhibitor of PFKFB3, which regulates the glycolytic pathway.