ADX-47273

Synonym: 851881-60-2; (S)-(4-Fluorophenyl)(3-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone

CAS Number: 851881-60-2
Compound CID: 11383075

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ADX-47273, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGlu5.

Molecular Weight

369.36

Molecular Formula

C₂₀H₁₇F₂N₃O₂

Targets

mGlu5: 0.17 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 73 mg/mL (197.63 mM); Water: insoluble; Ethanol: 29 mg/mL (78.51 mM)

Applications

ADX-47273 can be used for its ability to enhance the receptor’s activity in response to glutamate binding, potentially leading to downstream effects on synaptic transmission and neuronal function.