Properties
Description
ADX-47273, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGlu5.
Molecular Formula
C20H17F2N3O2
Solubility
DMSO: 73 mg/mL (197.63 mM); Water: insoluble; Ethanol: 29 mg/mL (78.51 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ADX-47273 can be used for its ability to enhance the receptor’s activity in response to glutamate binding, potentially leading to downstream effects on synaptic transmission and neuronal function.
Storage
Store at -20°C, and keep desiccated.
