AhR inhibitor, ITE, Purity ≥98%

Synonym: 448906-42-1; 2-[1H-Indol-3-yl(oxo)methyl]-4-thiazolecarboxylic acid methyl ester; Methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate; AhR inhibitor

MDL: MFCD06411597
CAS Number: 448906-42-1
Compound CID: 4668801

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ITE is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting AhR. The molecular weight of the compound is 286.31, and its molecular formula is C₁₄H₁₀N₂O₃S.

Molecular Weight

286.31

Molecular Formula

C₁₄H₁₀N₂O₃S

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Identity

Confirmed by NMR/HPLC/MS.

Applications

ITE displays the significant potential to act as an effective endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM.