Properties
Description
AKT-IN-2 inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, P70S6K, pGSK3β, PKA, PKCβ2, and RSK1.
Molecular Formula
C25H34F3N7O
Targets
Akt1: 5 nM; P70S6K: 399 nM; pGSK3β: 92 nM; PKA: 84 nM; PKCβ2: 3.98 nM; RSK1: 568 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AKT-IN-2 can be used to investigate the biological activities mediated by Akt signaling in cancer models.