Properties
Description
ARQ-092, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt1 E17K mutant, Akt2, Akt3, and Leishmania.
Molecular Formula
C27H24N6
Targets
Akt1: 2.7 nM; Akt1 E17K mutant; Akt2: 174 nM; Akt3: 8.1 nM; Leishmania
Solubility
DMSO: 8 mg/mL (18.49 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ARQ-092 is used to study its effect on cancer cells by targeting Akt.