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Akt inhibitor AT7867, Purity ≥98%
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Cat. No.: X24-05-ZQ192

Akt inhibitor AT7867, Purity ≥98%

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Synonym: 857531-00-1; AT-7867; Akt inhibitor

  • CAS Number: 857531-00-1
  • Compound CID: 11175137
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AT7867, soluble in DMSO and ethanol and insoluble in water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, PKA, Akt2, Akt3, c-Src, CDK2, Chk1, EGFR, FGFR3, GSK-3β, and MEK1.
Molecular Weight
337.9
Molecular Formula
C20H20ClN3
Targets
Akt1: 32 nM; PKA: 20 nM; Akt2: 17 nM; Akt3: 47 nM; c-Src: >1 μM; CDK2: >1 μM; Chk1: >1 μM; EGFR: >1 μM; FGFR3: >1 μM; GSK-3β: >1 μM; MEK1: >1 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 63 mg/mL (186.47 mM); Water: Insoluble; Ethanol: 5 mg/mL (14.79 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AT7867 can be utilized to explore its dual inhibition of Akt and p70S6 kinase in cancer research.
Publications
Publications (0)

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