Akt inhibitor AZD5363, Purity ≥98%

Synonym: 1143532-39-1; AZD 5363; AZD-5363; Akt inhibitor

CAS Number: 1143532-39-1
Compound CID: 25227436

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD5363, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt2, Akt3, Autophagy, P70S6K, PKA, ROCK1, and ROCK2.

Molecular Weight

428.9

Molecular Formula

C₂₁H₂₅ClN₆O₂

Targets

Akt1: 3 nM; Akt2: 7 nM; Akt3: 7 nM; Autophagy; P70S6K: 6 nM; PKA: 7 nM; ROCK1: 470 nM; ROCK2: 60 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (184.18 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD5363 can be used to study the therapeutic effects of Akt inhibition in various cancers.