Akt inhibitor BAY1125976, Purity ≥98%

Synonym: 1402608-02-9; BAY 1125976; BAY-1125976; Akt inhibitor

CAS Number: 1402608-02-9
Compound CID: 70817911

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY1125976, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt2, and Akt3.

Molecular Weight

383.45

Molecular Formula

C₂₃H₂₁N₅O

Targets

Akt1: 5.2 nM (IC₅₀, at 10 μM ATP); Akt2: 18 nM (IC₅₀, at 10 μM ATP); Akt3: 427 nM (IC₅₀, at 10 μM ATP)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (23.47 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

BAY1125976 is used to explore the inhibition of Akt and its effects on cancer cell proliferation.

Storage

Store at -20ºC.