Akt inhibitor BAY1125976, Purity ≥98%

Synonym: 1402608-02-9; BAY 1125976; BAY-1125976; Akt inhibitor

CAS Number: 1402608-02-9
Compound CID: 70817911

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY1125976, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt2, and Akt3.

Molecular Weight

383.45

Molecular Formula

C₂₃H₂₁N₅O

Targets

Akt1: 5.2 nM (IC₅₀, at 10 μM ATP); Akt2: 18 nM (IC₅₀, at 10 μM ATP); Akt3: 427 nM (IC₅₀, at 10 μM ATP)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (23.47 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BAY1125976 is used to explore the inhibition of Akt and its effects on cancer cell proliferation.