Properties
Description
CCT128930, soluble in DMSO and ethanol and insoluble in water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt2, p70 S6K, and PKA.
Molecular Formula
C18H20ClN5
Targets
Akt2: 6 nM; p70 S6K: 120 nM; PKA: 168 nM
Solubility
DMSO: 59 mg/mL (172.59 mM); Water: Insoluble; Ethanol: 5 mg/mL (14.63 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CCT128930 is used to investigate Akt inhibition and its consequences for cancer growth and survival.