Properties
Description
CCT128930, soluble in DMSO and ethanol and insoluble in water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt2, p70 S6K, and PKA.
Molecular Formula
C18H20ClN5
Targets
Akt2: 6 nM; p70 S6K: 120 nM; PKA: 168 nM
Solubility
DMSO: 59 mg/mL (172.59 mM); Water: Insoluble; Ethanol: 5 mg/mL (14.63 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CCT128930 is used to investigate Akt inhibition and its consequences for cancer growth and survival.