Akt inhibitor GSK2141795, Purity ≥98%

Synonym: 1047634-65-0; GSK2141795; GSK2141795; Uprosertib; GSK 795; Uprosertib; GSK795; Akt inhibitor

CAS Number: 1047634-65-0
Compound CID: 51042438

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK2141795, soluble in DMSO and ethanol and insoluble in water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt2, and Akt3.

Molecular Weight

429.25

Molecular Formula

C₁₈H₁₆Cl₂F₂N₄O₂

Targets

Akt1: 180 nM; Akt2: 328 nM; Akt3: 38 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 80 mg/mL (186.36 mM); Water: Insoluble; Ethanol: 80 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK2141795 is used to investigate the broad-spectrum inhibition of Akt in cancer research.