Akt inhibitor GSK690693, Purity ≥98%

Synonym: 937174-76-0; GSK-690693; Akt inhibitor

CAS Number: 937174-76-0
Compound CID: 16725726

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK690693, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets PKCη, PKCθ, Akt1, Akt2, Akt2, PKA, PKCβ, PKCδ, PKCε, and PKG1β.

Molecular Weight

425.5

Molecular Formula

C₂₁H₂₇N₇O₃

Targets

PKCη: 2 nM; PKCθ: 2 nM; Akt1: 2 nM; Akt2: 13 nM; Akt2: 9 nM; PKA: 24 nM; PKCβ: 19 nM; PKCδ: 14 nM; PKCε: 21 nM; PKG1β: 33 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 36 mg/mL (84.61 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK690693 can be used to study the impact of Akt inhibition on cancer and tumor progression.