Akt inhibitor GSK690693, Purity ≥98%

Synonym: 937174-76-0; GSK-690693; Akt inhibitor

CAS Number: 937174-76-0
Compound CID: 16725726

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK690693, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets PKCη, PKCθ, Akt1, Akt2, Akt2, PKA, PKCβ, PKCδ, PKCε, and PKG1β.

Molecular Weight

425.5

Molecular Formula

C₂₁H₂₇N₇O₃

Targets

PKCη: 2 nM; PKCθ: 2 nM; Akt1: 2 nM; Akt2: 13 nM; Akt2: 9 nM; PKA: 24 nM; PKCβ: 19 nM; PKCδ: 14 nM; PKCε: 21 nM; PKG1β: 33 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 36 mg/mL (84.61 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK690693 can be used to study the impact of Akt inhibition on cancer and tumor progression.

Storage

Store at -20ºC.