Cat. No.: X24-05-ZQ038
Akt inhibitor PF-04691502, Purity ≥98%
Synonym: 1013101-36-4; PF04691502; Akt inhibitor
- CAS Number: 1013101-36-4
- Compound CID: 25033539
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
PF-04691502, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets PI3Kα, PI3Kγ, mTOR, P-Akt(S473), P-Akt (T308), PI3Kβ, and PI3Kγ.
Molecular Formula
C22H27N5O4
Targets
PI3Kα: 1.8 nM (Ki); PI3Kγ: 1.9 nM (Ki); mTOR: 16 nM (Ki); P-Akt(S473): 3.8 nM; P-Akt (T308): 7.5 nM; PI3Kβ: 2.1 nM (Ki); PI3Kγ: 1.6 nM (Ki)
Solubility
DMSO: 13 mg/mL (30.55 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-04691502 is used to research the inhibition of the PI3K/mTOR pathway and its effects on tumor growth.
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