Akt inhibitor PHT-427, Purity ≥98%

Synonym: 1191951-57-1; PHT427; Akt inhibitor

CAS Number: 1191951-57-1
Compound CID: 44240850

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PHT-427, soluble in DMSO and ethanol and insoluble in water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt and PDK-1.

Molecular Weight

409.6

Molecular Formula

C₂₀H₃₁N₃O₂S₂

Targets

Akt: 2.7 μM (Ki); PDK-1: 5.2 μM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (183.1 mM); Water: Insoluble; Ethanol: 55 mg/mL (134.27 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PHT-427 can be used to investigate the effects on AKT and PDK1 signaling, providing insights into cancer treatment mechanisms.