Properties
Description
Triciribine inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt (PC3 cells) and HIV-1 (CEM-SS, H9, H9IIIB, U1 cells).
Molecular Formula
C13H16N6O4
Targets
Akt (PC3 cells): 130 nM; HIV-1 (CEM-SS, H9, H9IIIB, U1 cells): 20 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Triciribine is used to inhibit AKT signaling, providing a tool to study its role in cancer and other diseases.