Properties
Description
Brigatinib, soluble in warmed DMSO and warmed ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against ALK.
Molecular Formula
C29H39ClN7O2P
Solubility
Warmed DMSO: 1 mg/mL (1.71 mM); Water: Insoluble; Warmed ethanol: 39 mg/mL (66.76 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Brigatinib is an ALK inhibitor effective in studying resistances and treatments for ALK-positive non-small cell lung cancer (NSCLC).
