Properties
Description
Almorexant HCl, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets OX1 receptor, and OX2 receptor.
Molecular Formula
C29H32ClF3N2O3
Targets
OX1 receptor: 6.6 nM; OX2 receptor: 3.4 nM
Solubility
DMSO: 62 mg/mL (112.93 mM); Water: insoluble; Ethanol: 44 mg/mL (80.14 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Almorexant HCl can be used for its ability to improve overall sleep quality and promote restorative sleep in individuals with sleep disturbances.
Storage
Store at -20°C, and keep desiccated.