Properties
Description
Almorexant HCl, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets OX1 receptor, and OX2 receptor.
Molecular Formula
C29H32ClF3N2O3
Targets
OX1 receptor: 6.6 nM; OX2 receptor: 3.4 nM
Solubility
DMSO: 62 mg/mL (112.93 mM); Water: insoluble; Ethanol: 44 mg/mL (80.14 mM)
Applications
Almorexant HCl can be used for its ability to improve overall sleep quality and promote restorative sleep in individuals with sleep disturbances.