Properties
Description
Alniditan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1B receptor, 5-HT1D receptor, human 5-HT1B receptor, and human 5-HT1D receptor.
Molecular Formula
C17H26N4O
Targets
5-HT1B receptor: 0.9 nM (Kd); 5-HT1D receptor: 1.2 nM (Kd); Human 5-HT1B receptor: 1.7 nM (IC50, in HEK 293 cell); Human 5-HT1D receptor: 1.3 nM (IC50, in HEK 293 cell)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Alniditan can be studied for its effect on reducing the frequency and severity of migraine attacks.
Storage
Store at -20°C, and keep desiccated.
