Amcasertib, Purity ≥98%

Synonym: 1129403-56-0; BBI 503; BBI-503; N-[2-(Diethylamino)ethyl]-2,4-dimethyl-5-[(Z)-[2-oxo-5-(2-phenyl-1,3-thiazol-4-yl)-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxamide

CAS Number: 1129403-56-0
Compound CID: 25190990

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Amcasertib, soluble in DMSO and ethanol and insoluble in water, is claimed to inhibit Nanog and other CSC pathways. The molecular weight of the compound is 539.69, and its molecular formula is C₃₁H₃₃N₅O₂S.

Molecular Weight

539.69

Molecular Formula

C₃₁H₃₃N₅O₂S

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 14 mg/mL (25.94 mM); Water: insoluble; Ethanol: 1 mg/mL (1.85 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Amcasertib plays a key role in modulating the cell cycle and apoptosis pathways.