Properties
Description
AMG-073 HCl (cinacalcet HCl), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets CaSR.
Molecular Formula
C22H23ClF3N
Solubility
DMSO: 67 mg/mL (170.1 mM); Water: insoluble; Ethanol: 28 mg/mL (71.09 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AMG-073 HCl (cinacalcet HCl) can be used for its effect on binding to and activating calcium-sensing receptors on the parathyroid gland.
Storage
Store at -20℃, and keep desiccated.