Properties
Description
Fumagillin, soluble in DMSO and warmed ethanol and insoluble in water, impedes the function of aminopeptidases, enzymes involved in protein processing and degradation. It targets MetAP2.
Molecular Formula
C26H34O7
Solubility
DMSO: 86 mg/mL (187.55 mM); Water: Insoluble; Warmed ethanol: 30 mg/mL (65.42 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Fumagillin serves to study angiogenesis, especially the formation of new blood vessels, often used in cancer research to inhibit tumor growth.
