Properties
Description
IEM 1754 dihydrobromide, soluble in DMSO and water and insoluble in ethanol, modulates the activity of AMPA receptors, which are critical for fast synaptic transmission in the central nervous system. It targets GluR1 and GluR3.
Molecular Formula
C16H30N2.2HBr
Targets
GluR1: 6 μM; GluR3: 6 μM
Solubility
DMSO: 80 mg/mL (194.05 mM); Water: 80 mg/mL (194.05 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IEM 1754 dihydrobromide serves as an AMPA receptor inhibitor to explore synaptic functions and memory processes.