Properties
Description
A-769662, soluble in DMSO and insoluble in ethanol and water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets AMPK and fatty acid synthesis.
Molecular Formula
C20H12N2O3S
Targets
AMPK: 0.8 μM (EC50); Fatty acid synthesis: 3.2 μM
Solubility
DMSO: 65 mg/mL (180.36 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
A-769662 is employed to activate AMPK and analyze its effects on metabolism and cancer.
