Properties
Description
BML-275, soluble in warmed DMSO and warmed ethanol and insoluble in water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets AMPK.
Molecular Formula
C24H25N5O
Targets
AMPK: 109 nM (Ki)
Solubility
Warmed DMSO: 1 mg/mL (2.5 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
BML-275 is used to inhibit AMPK and study its impact on metabolic pathways and cancer.