Properties
Description
ex229, soluble in DMSO and insoluble in ethanol and water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets AMPK α1β1γ1, AMPK α1β1γ1, and AMPK α2β1γ1.
Molecular Formula
C24H18ClN3O3
Targets
AMPK α1β1γ1: 0.06 μM (Kd); AMPK α1β1γ1: 0.51 μM (Kd); AMPK α2β1γ1: 0.06 μM (Kd)
Solubility
DMSO: 11 mg/mL (25.47 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ex229 is used to study AMPK activation and its potential therapeutic applications.
