Properties
Description
MK-3903, soluble in DMSO and insoluble in ethanol and water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets AMPK.
Molecular Formula
C27H19ClN2O3
Targets
AMPK: 8 nM (EC50)
Solubility
DMSO: 82 mg/mL (180.26 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MK-3903 can be utilized for researching the activation of AMP-activated protein kinase (AMPK) in metabolic disorders.