AMPK inhibitor PF-06409577, Purity ≥98%

Synonym: 1467057-23-3; PF06409577; PF 06409577; AMPK inhibitor

CAS Number: 1467057-23-3
Compound CID: 71748255

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-06409577, soluble in DMSO and ethanol and insoluble in water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets AMPK α1β1γ1.

Molecular Weight

341.79

Molecular Formula

C₁₉H₁₆ClNO₃

Targets

AMPK α1β1γ1: 7 nM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (184.32 mM); Water: Insoluble; Ethanol: 63 mg/mL (184.32 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-06409577 is used in research focusing on the selective inhibition of protein tyrosine phosphatase 1B (PTP1B) for metabolic diseases.