AMPK inhibitor WZ4003, Purity ≥98%

Synonym: 1214265-58-3; WZ 4003; WZ-4003; AMPK inhibitor

CAS Number: 1214265-58-3
Compound CID: 72200024

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WZ4003, soluble in DMSO and insoluble in ethanol and water, downregulates metabolic and energy homeostasis pathways, affecting cellular energy balance and potentially influencing cancer and metabolic disorders. It targets NUAK1 and NUAK2.

Molecular Weight

496.99

Molecular Formula

C₂₅H₂₉ClN₆O₃

Targets

NUAK1: 20 nM; NUAK2: 100 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 7 mg/mL (14.08 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

WZ4003 can be used to investigate the inhibition of salt-inducible kinases (SIKs) in immune and metabolic disorders.

Storage

Store at -20ºC.