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Anticoagulant heparin solution is a medicated solution that contains heparin, an active ingredient that prevents the formation of blood clots by blocking a key step in the blood clotting process. In addition to its anticoagulant effects, heparin has other important physiological functions. For example, it plays an important role in the regulation of cell proliferation, immune response, and control of inflammatory response in vivo. Therefore, the analysis of anticoagulant heparin solution holds significant importance in the field. CD BioGlyco provides a full range of anticoagulant heparin solution analysis services to clients with our advanced technology and extensive experience in Pharmaceutical Analysis.
Fig.1 Technologies for anticoagulant heparin solution analysis service. (CD BioGlyco)
Technology: Surface plasmon resonance
Journal: Analytical Biochemistry
IF: 3.191
Published: 2017
Results: This article describes a new method for measuring the anticoagulant activity of heparin using the surface plasmon resonance (SPR) technique. The method assesses the anticoagulant activity of heparin by measuring the interaction between heparin and antithrombin III (AT). Specifically, the researchers immobilized heparin on the SPR chip and observed its binding to heparin by injecting an antithrombin III solution. By monitoring the degree of binding between heparin and AT, the anticoagulant activity of heparin can be accurately measured. This method is rapid, sensitive, and accurate, and can provide a new option for the measurement of heparin anticoagulant activity.
Fig.2 Diagram of SPR solution competition experiment for anticoagulant activity measurement of heparin samples. (Zhao, et al., 2017)
In brief, CD BioGlyco is a dependable ally for individuals in need of trustworthy anticoagulant heparin analysis services. We are leading the way in this domain and are fully prepared to make substantial contributions toward enhancing healthcare through efficient analytical solutions. For further details, please don't hesitate to contact us.
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