Aprocitentan

Synonym: 1103522-45-7; ACT-132577; ACT132577; ACT 132577

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Aprocitentan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ETA, ETA, ETB, and ETB.

Molecular Weight

546.19

Molecular Formula

C₁₆H₁₄Br₂N₆O₄S

Targets

ETA: 3.4 nM; ETA: 6.7 (pA2); ETB: 987 nM; ETB: 5.5 (pA2)

Form

Lyophilized powder

Purity

>98%

Applications

Aprocitentan can be studied for its effect on lowering blood pressure.