Properties
Description
Aprocitentan inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ETA, ETA, ETB, and ETB.
Molecular Formula
C16H14Br2N6O4S
Targets
ETA: 3.4 nM; ETA: 6.7 (pA2); ETB: 987 nM; ETB: 5.5 (pA2)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Aprocitentan can be studied for its effect on lowering blood pressure.
Storage
Store at -20°C, and keep desiccated.
