Properties
Description
AS2521780 blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PKCα, PKCδ, PKCε, and PKCθ.
Molecular Formula
C30H41N7OS
Targets
PKCα: 160 nM; PKCδ: 160 nM; PKCε: 18 nM; PKCθ: 0.48 nM
Applications
AS2521780 can be used to help develop potential therapeutic strategies for certain diseases, such as inflammatory disease, fibrotic diseases, and cancer.