Properties
Description
Asarinin can decrease peripheral blood concentration of interleukin (IL)-12 and inhibit the expression of Toll-like receptor 4 (TLR4) and chemokine (C-X-C motif) receptor 3 (CXCR3), which means asarinin may have a role on TLR4 pathway and produced prolongation of allograft heart survival.
Molecular Formula
C20H18O6
Source
The dried herba of Asarum sieboldii Miq.
Purity
>98%, determined by HPLC.
Solubility
It is soluble in boiling methanol, ethanol, chloroform, acetone and benzene, and practically insoluble in water.
Identity
Confirmed by NMR and MS.
Applications
Asarinin can be used for immunosuppression activity experiments, etc.
