Properties
Description
AZ-20, soluble in DMSO, water and ethanol, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATR and mTOR.
Molecular Formula
C21H24N4O3S
Targets
ATR: 5 nM; mTOR: 38 nM
Solubility
DMSO: 80 mg/mL (193.93 mM); Water: 5 mg/mL (38.11 mM); Ethanol: 3 mg/mL (7.27 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZ-20 can be used to study its effects as an ATR kinase inhibitor in DNA repair and cancer research.
