Properties
Description
AZ31, soluble in DMSO and insoluble in ethanol and water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells.
Molecular Formula
C24H28N4O3
Solubility
DMSO: 46 mg/mL (109.39 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ31 is applied in studies on the inhibition of ATR and its role in cellular response to genotoxic stress.