Properties
Description
AZD1390, soluble in DMSO and ethanol and insoluble in water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATM.
Molecular Formula
C27H32FN5O2
Solubility
DMSO: 14 mg/mL (29.31 mM); Water: Insoluble; Ethanol: 93 mg/mL (194.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZD1390 is applied in preclinical studies to explore its potent ATM inhibition in enhancing radiotherapy responses.
