Properties
Description
AZD6738, soluble in DMSO and warmed ethanol and insoluble in water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATR.
Molecular Formula
C20H24N6O2S
Solubility
DMSO: 75 mg/mL (181.81 mM); Water: Insoluble; Warmed ethanol: 38 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZD6738 can be employed to study the inhibition of ATR kinase in cancer therapy, particularly in combination with other DNA-damaging agents.
