Properties
Description
CGK 73, soluble in DMSO and insoluble in ethanol and water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets ATR and ATM.
Molecular Formula
C23H18Cl3FN4O3S
Solubility
DMSO: 90 mg/mL (161.91 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CGK 73 is utilized to investigate the mechanisms of guanylyl cyclase activation in cardiovascular research.