ATM-ATR inhibitor KU-55933, Purity ≥98%

Synonym: 587871-26-9; KU55933; ATM-ATR inhibitor

CAS Number: 587871-26-9
Compound CID: 5278396

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KU-55933, soluble in DMSO and insoluble in ethanol and water, interferes with DNA damage response and repair processes, enhancing the sensitivity of cancer cells. It targets DNA-PK, mTOR, ATM, ATR, PI3K, and PI4K.

Molecular Weight

395.5

Molecular Formula

C₂₁H₁₇NO₃S₂

Targets

DNA-PK: 2.5 μM; mTOR: 9.3 μM; ATM: 12.9 μM; ATR: >100 μM; PI3K: 16.6 μM; PI4K: >100 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 29 mg/mL (73.33 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

KU-55933 is utilized to investigate ATM kinase inhibition in cancer research and DNA damage response.